For the thousands of children and young adults worldwide who are afflicted with NPC and for the 60,000 children who have other neurodegenerative diseases, the APMRF’s goal means life. This research effort is a race against time.  Medical research is costly, but it’s our hope in saving the lives NPC patients.

The Parseghian Fund currently funds multiple labs around the world. This funding supports an international research program:

• To expedite a treatment and cure for NPC disease
• To promote collaborative NPC research efforts among the world’s leading experts in cholesterol metabolism, cell biology, neurobiology, genetics, pharmacology and other areas of science
• To study NPC disease that may also further the cause of other neurodegenerative diseases as well as cholesterol storage disorders

The research program is directed by a Scientific Advisory Board (SAB) of internationally acclaimed scientists.

The 2025 Request for Proposals is outlined below

Applying for Grants

The mission of the APMRF is to promote research that furthers understanding of the molecular basis of Niemann Pick Type C disease and targets development of novel strategies to treat and/or cure the disease.  For more information please read the rest of the RFP including the General Information section.

2025 Request for Proposals (RFP) research grants will provide support for up to $125,000 for the period of one year beginning July 1, 2025.

Please submit a proposal through the electronic portal by April 15^th, 2025. Formatting for the online submission is outlined below.

Your online submission will include:

• Abstract (250 words)
• Biosketch
• Preliminary Data (250 word max or 1 page with figures)
• Program Goals (250 word Max)
• Specific Aims (400 word max)
• Prosposed impact of Grant (150 word max)

Start the Grant submission process by clicking on this Link

**Please note that the submission form cannot be saved and resumed later. We recommend drafting your information in advance to ensure a smooth upload and submission process. Thank you for your understanding as we transition to our new system. If you are having trouble, please reach out to Sean Kassen at skassen@nd.edu. 

All submissions will be reviewed by the Science Advisory Board by June 10, 2025 and those recommended for research awards will be notified by June 18. Upon notification a detailed budget will then be requested and signing of a grant contract will be required with your institution.

Grant submission deadline is April 15, 2025

*Please make sure you receive an email confirmation from me by April 16th, 2025.  If you do not receive one, please call me at 574-631-4689.

More information about grant process